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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b007a34a174a4f4b9662708075b962336aecf14b31191552a50120ed2120b32' 
  AND token = 'lW2T0C2vt47qj+VFtwEdDErgHjtK2DOHmE20X2GNyao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}