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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e93b7c98965da535f638b059530968fcac05df6d2de3a455b1f343a3e49d5ff' 
  AND token = 'jfXM/AHTeJoAI5pxT7d0AOHYAQxeYrnxhnoSzo2nzQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}