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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d35655dd98b3669d337996a85c323ab0ce03b3fc12201a5146430622711427d' 
  AND token = 'LvEH/RowYBWy4LiB8ObpfDorDcta1iIgLSE0kQZqw8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}