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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecca6b6223c47a322308501f8047cb0c120827b5908c85b5c302fb24bda4e0b9' 
  AND token = 'MTSuF6sWru5+9Do2k0Z8F3LbgwKW61X3gYmDAS0YMnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}