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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a018df19c79ef13eb5e08de0579eecdf3724c65490fbe387ba14aca88dffcc2' 
  AND token = 'MnsyyUyu4FeI4/kqpFt6hgOg55KsSKtnZURdd2S26mY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}