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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d3ea2fc8f3ce67adbc492f052c7c5cdd037fc4bc7b88c8769c3c4f920a6e314' 
  AND token = 'xm8iqNypkdOELkVl/FrPq8fkov0KLvMc2SWF/QFfe58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}