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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e25105f712e03bbb02d9ee44457cfa3edfd2a6b3930429f1ba4335e72e31a718' 
  AND token = 'NtyKQGe2TTddHi18BIEG0u3kIUJU2JUT4mtUnBXUlyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}