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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14fcc335dd6dfbe458c77af7bb854a31670ccb0b04d70c9d6984e14697b2869d' 
  AND token = 'k4pKFBmf9UUJMPIn+BOuO/YQeIIWQ3fsKwHa1rPDc+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}