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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b88ee943924ede957b77a8b65acdda71c7c26c3a2e60024ea67a7bedd05782f2' 
  AND token = '5HaOKXY33W1//UjUPEgV0+EP/75wzUcQDGgi3+PCgls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}