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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '918aa6e5d9ce56ccd49a7b100d31eb3bc5389b815540c443de65d6733d71d43f' 
  AND token = 'BsC3kzp7SbRnaFr5X43pS5S1y0TiG2YojkdhSKyQNao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}