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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af82df34b4d2c7e3bcac0490803658654070c846b8bbbff2429e39e32cd8e856' 
  AND token = 'bC3Ce8xZ2nPJY9qfOlSXTX+P1m2pG7pupya2KHXcWiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}