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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1410e4cce8e44a152799507d118c0d20f0b00608957f066f30b5a8929055ac9e' 
  AND token = '1IiZcBQzfTxfVII8gf6KI9xz+YUvtTCNfjI0FH5MWPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}