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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cf3ac48a33fc1e7cc05d60bb919c860d96a3d6d81553abab46f59937e747d15' 
  AND token = 'MseMCAxL+XEmECZ+Q3KFKS39hxXuoEk/Z9WHwbIT/0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}