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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c41388fc2cf1df7b7bcc5fe436187aa6e03f2149d377a35a2221f61b26c2282' 
  AND token = 'BCXc1/izXZtRdEfe/TlUIJKEg75XPOzsI/3gOeKx7IA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}