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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '745795d06075a2e80e6c3b5a4a66788098c66991be30325e5367ce24656ec110' 
  AND token = '65ZKUWfZjcHHtd85NvJkB0mWuA0COHOBH+7jREci6wQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}