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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f635deca66b09fc21a2f776b84b538b9fb212b0f4986fe9850cfae83fa864397' 
  AND token = 'ux2i/qQrJlMSZeTIgyHuCONs7fF0gb/YSzqIV06ycSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}