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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19de1c90597fd4842847a587f45b20c009d67b0ddd0d0ee57fdfce6ccde9a063' 
  AND token = '+/lEc0Jga6Hd/oQKvEPot3L5RwAZEDPMxQfj3lbT0/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}