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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c9a0bbd85e890874581192d9cd69710e67cd5bfe0a0a6ae5dc3ad0727f7b860' 
  AND token = 'EOnqdpJw2aVU0vYkzjf+75w/e0RYNk3Z7zoCFyDNqno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}