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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd3b2bfa15ba0154862ecd3159cd01e168544778a7f4594b18056bf856650be8' 
  AND token = 'r4/VIOqwHYpRPV59+uNAoc6WM8rZAAnNvLbpIDQS2vI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}