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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f2b1166e67b3b765fc48bfcab85cbf28aab6753caa4078c5bdbf8a6c7d5353e' 
  AND token = 'Cw5uULCJSFsHDh5ASV7NK+RFRxyEkJsKrYM3KpsCT+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}