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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '024e7206c8d18458adc1014fba81be45ce2ff6d8c333af5b44e1e5cff391e237' 
  AND token = 'uOWEtBRDBGZteLyakzcjqmqwVa03kwTeHx0VNC46Bq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}