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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5f196b47d5228275c9a252fb490c5201514396af29d6bce57cd8582b7692dd4' 
  AND token = 'jsVJA2kPpptoyCpgS+OVRFkxdImdAG62Od98jCiXG5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}