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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9317721430894af9a80e7393951ac3e66555a551cb472c66edf0e420e21d534e' 
  AND token = 'I7pyH5Up7QczAhhaqYxowvLCsVrYmP/BU75LQYQhdno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}