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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e5629dd612b29d8427393639247ea8e46802a90aed93e53ab1ce08734c309ff' 
  AND token = 'i4gNBWCeoLyf88DDhj+ooa0w0HKFTds3Rm3ICpcfBg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}