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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f08b3203c9dc9a3b13f55a6ef4507717305575878859a6d81e3660a6a1f7488' 
  AND token = 'ZeXDwq14JWiwuqgM1GN2eEgLCXbq51TgtR9ZVxlqFWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}