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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74ed5a37149e683b9a13c186e801862c1fe92665b0cd6b9f69dc882ed229b70e' 
  AND token = '8YM+zWuHoOUuaUSnoTQoeBARGbKuj520UYbrihlzJpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}