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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c1c6345d56fe91fe511806221c29691b0842261730765a7c14b9b8509908062' 
  AND token = 'rcoNiOSKJ703gQ7YSSi8oklgkLp1wtDcKp9gad1qMvk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}