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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '535f46b77f78deb5fa14e199242d2a1104e6b8f4b2b4054523acc1dc0957149a' 
  AND token = 'SOnlHFQXeeIOQp8SV/axX85Bt7IOMYrfj7nGcQ/3CyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}