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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '438c5d2a327732f0212c83905a990341554f04ac81c143bba709a56925db1a5b' 
  AND token = 'SI9XJzvdjG4f+rBWUpE2T6LDv0y1OlgMPI6oxpF2Zr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}