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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d4ee48103a42e1038816b12e660b6e3f7c884c3c754a4f4c50ac1b091153fd4' 
  AND token = 'RYt7sxvSW7jTbYxK71y183wnnHLTsu7fbvmRE3dFd44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}