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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c61f26328a2f657bb151dd5b41cf94e6b427def18ec5b3bb3faee26d3ef5aa29' 
  AND token = 'fSg5v5HrUA2fyWq5MJyFmbf5uW+9ZsV8GcilJVEUXOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}