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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e400fa4336337da4f162f3fded91b784ed10f3365a673e6be3648ae3124e705' 
  AND token = 'OObHuEhTm33kJLFzJIWQ8LUddX2vypWL7v5xXm3McPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}