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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b635aadf1e9c38d772ded79abcaf5e761d02f0d31c852d4e4392176fe88a405' 
  AND token = 'k1T8Dr5ilFM34Jjn+5qu58dAcOEthEfO0zyUMDIoKBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}