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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4b7b4a489a68cb40fd8efb1f30d0bebfdde8d652752140d975c9050602f10d2' 
  AND token = 'ES8TWGQwVu/d5Oh0VWQHhkV026U4ZfO9VvMeJa5q+ks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}