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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f79336b3a15a99ff04aa69dfac46b64c9f12a04ede497e13755cde1fe0fbbf61' 
  AND token = 'Z+Egxf5YQfuA91hqZ9a1FwHrq9cfvLCfDkd+AWlvNTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}