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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50acad62f6e3b97b2d9af72b737dfd40e7ed10522efbe3dfe2807605e5799bc0' 
  AND token = 'cz9nrgiiImwcKHFm3fwDpMfN3bRpONjP27PixwXdbts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}