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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bdbb7a89cfe35e8bf7214959a64d1aa61b26124cc058054ed85de2725868174' 
  AND token = 'z4g6Tso9i6Tgx4Vi7cJtzONiAmU6XZGIBf6ganyOKAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}