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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f48c6cf4f436c6e566e50b802b8da150842075fe5ddcaac97df7744de815b70c' 
  AND token = 'tBJ07i/cLD8bA01t7V0SgpwjqFy5fkT+kAhELxORc18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}