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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afcf256d20d53fb831d1bc1d02e03176af8a3eb0e3b169bf469c78f6158df7a9' 
  AND token = 'mrvTgeD96012FQ4/AOKqvE12E+DsOpHqkmlLuvRtHsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}