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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16eb131c88471dd38b255e76e96f3df38aad591ac89544bee9660e8a3f96cf1a' 
  AND token = 'UOphthcePCbd+QC0YnsqjyI0unweMekUwFplmxVKJw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}