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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '349a9773c2163f46663eae5a960ca9dc9cdc0a67d9175486930841864a6ee25a' 
  AND token = 'cVnjYDQ5HBmdNVQ/Hd/pDvJfwi8/1bodgwTmvO8OvL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}