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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac4f1f800a33c900a3b40754733860d0387de58906c95ab75b81ced6896095f2' 
  AND token = 'p5vP8hXYN3WIfTSitG5KCQbKbK3VKVUDOUk1XVYqKIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}