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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6112b1a21d25c57aad993a38207920b6497ad6ac40623e704c00e87864987b78' 
  AND token = 'X0hLv/HdsTTRYx2SumHolDNLCWJnWuDQ9qHcVqPLM4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}