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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb1ad927808e904111a6bad8885464ff5318f9068e3a36ddb588ef4e2ca2c372' 
  AND token = 'UsxKSkm/N3QibhL5mxNDbL/5hmx6nVgpG7Vhr8tCO64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}