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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '905fac401d454579f9186ced1134595f8f04f049dce5f3e7b4e0c5ffa51c0de8' 
  AND token = 'bw08EoOX5RPUVoV9aAMMO1eElNz8g3SGwKLwrwQF8is=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}