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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10fc9e364d3e9c1187aa4c962d872e318e73ae18b502a53b8cafc87b7c13e591' 
  AND token = 'mwJS6j1czW+wFcSWz/gbbCRy31A19V0JdHLPOa1NalU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}