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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b51e410cf512be509260ff0958fbd7d36a1840b295ab6122e522907c447cd48f' 
  AND token = 'lwfUL5jsFlsZTSiv/iqsiDgZark+5RL5nPnx2ln5NHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}