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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e1c7c2e53c1194f4888c3e26d11dea0ba79fffe781b345ea9db43cc93221e0d' 
  AND token = '5TAqCMvAFRyNalP5Ikt2wYlrQ3ufq5EkMArxKhgxsY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}