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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4413cede8e212e9340c8ffb03054d8f99f658e9db51dbfc75486492adedc7187' 
  AND token = '1ESprPWlyr47yMU35XJHUoO9++R0p2x1PRSNV5E4pRg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}