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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da4ba66d925c621e8c8d14f15baff11e89ec35ab2ca8f0e333080c1018a0f1c4' 
  AND token = 'tkNSdMPbR7pB5u0PD2+1oZwIEewFeh4hLwIBvDQEUVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}